Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia
Identifieur interne : 002551 ( Main/Exploration ); précédent : 002550; suivant : 002552Ultrasound‐guided injection of the iliopsoas muscle with botulinum toxin in camptocormia
Auteurs : Rainer Von Coelln [Allemagne] ; Armin Raible [Allemagne] ; Thomas Gasser [Allemagne] ; Friedrich Asmus [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-04-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Anti-Dyskinesia Agents (therapeutic use), Bontoxilysin, Botulinum Toxins (therapeutic use), Dorsal spine, Female, Guidance, Humans, Iliopsoas muscle, Kyphosis, Male, Nervous system diseases, Parkinson Disease (complications), Parkinson Disease (drug therapy), Psoas Muscles, Treatment Outcome, Ultrasound, botulinum toxin A, camptocormia, iliopsoas, psoas major, ultrasound‐guidance.
- MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins.
- complications : Parkinson Disease.
- drug therapy : Parkinson Disease.
- Aged, Female, Humans, Male, Psoas Muscles, Treatment Outcome.
Abstract
Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco‐lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound‐guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500–1,500 MU of BTX per side in 4–6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow‐up visits, as well as self‐assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism‐associated camptocormia. © 2008 Movement Disorder Society
Url:
DOI: 10.1002/mds.21967
Affiliations:
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Le document en format XML
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<term>Dorsal spine</term>
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<term>Guidance</term>
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<term>Iliopsoas muscle</term>
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<term>Nervous system diseases</term>
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<term>Parkinson Disease (drug therapy)</term>
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<front><div type="abstract" xml:lang="en">Camptocormia is characterized by an abnormal posture of the trunk with pronounced flexion of the thoraco‐lumbar spine during standing and walking, which abates in a supine position. Treatment options for camptocormia are limited and mostly futile. Here, we report on the ultrasound‐guided ventral injection of botulinum toxin A (BTX) into deep portions of the iliopsoas muscle in four parkinsonian patients with camptocormia as chief complaint. Using this novel and safe application technique, all patients received 500–1,500 MU of BTX per side in 4–6 month intervals. Treatment was generally well tolerated. At the highest dose, all patients complained of mild weakness of hip flexion. Standardized physical exam at follow‐up visits, as well as self‐assessment of patients, failed to show a relevant and lasting improvement of posture. In conclusion, injection of BTX into the iliopsoas does not appear to be a promising approach for the treatment of parkinsonism‐associated camptocormia. © 2008 Movement Disorder Society</div>
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